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Sigma Aldrich S-Acetylthioglycolic acid N-hydroxysuccinimide ester

Catalog No. A904350MG Shop All MilliporeSigma Sigma Organic Chemistry Products
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MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

  • Thiolating reagent for primary amines; thiol can be deprotected under mild conditions
  • Typically, couples initially to a molecule containing primary amine by amide bond buffered at pH 7.5
  • Deprotection may be accomplished with 0.05 m hydroxylamine at neutral pH
  • Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.note that the ester couples very efficiently to primary amines compared to other thiolating reagents
  • In addition, this reagent will neutralize original amine positive charge

Specifications

CAS 76931-93-6
Molecular Formula C8H9NO5S
Linear Formula C8H9NO5S
MDL Number MFCD00036891
Quantity 50 mg
Synonym N-Succinimidyl (acetylthio)acetate; N-Succinimidyl S-acetylthioglycolate; S-Acetylthioglycolic acid NHS ester; SATA
Molecular Weight (g/mol) 231.23
Percent Purity ≥95% (TLC)
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