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Sigma Aldrich S-Acetylthioglycolic acid N-hydroxysuccinimide ester
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Description
- Thiolating reagent for primary amines; thiol can be deprotected under mild conditions
- Typically, couples initially to a molecule containing primary amine by amide bond buffered at pH 7.5
- Deprotection may be accomplished with 0.05 m hydroxylamine at neutral pH
- Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.note that the ester couples very efficiently to primary amines compared to other thiolating reagents
- In addition, this reagent will neutralize original amine positive charge
Specifications
Specifications
| CAS | 76931-93-6 |
| Molecular Formula | C8H9NO5S |
| Linear Formula | C8H9NO5S |
| MDL Number | MFCD00036891 |
| Quantity | 50 mg |
| Synonym | N-Succinimidyl (acetylthio)acetate; N-Succinimidyl S-acetylthioglycolate; S-Acetylthioglycolic acid NHS ester; SATA |
| Molecular Weight (g/mol) | 231.23 |
| Percent Purity | ≥95% (TLC) |
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