Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Benzyl Derivatives
  8. (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%

(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%

Catalog No. AAB23117ME
Change view
Click to view available options
Quantity:
500 mg
2.5 g
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
AAB23117ME 500 mg
AAB2311788 2.5 g
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
Catalog No. AAB23117ME Supplier Thermo Scientific Chemicals Supplier No. B23117ME
Only null left
Add to Cart

Description

CAS: 17257-71-5 | C10H8F3O3 | 233.17 g/mol

(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is used as a chiral derivatizing agent, it reacts with an alcohol or amine of unknown stereochemistry to form an ester or amide. The absolute configuration of the ester or amide is then determined by proton and/or 19F NMR spectroscopy.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is used as a chiral derivatizing agent, it reacts with an alcohol or amine of unknown stereochemistry to form an ester or amide. The absolute configuration of the ester or amide is then determined by proton and/or 19F NMR spectroscopy.

Solubility
Readily soluble in hexane, ether, THF, CH2Cl2, benzene.

Notes
Hygroscopic. Store under inert gas. Store away from oxidizing agents, moisture.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 17257-71-5
Molecular Formula C10H8F3O3
Molecular Weight (g/mol) 233.17
MDL Number MFCD00064200
InChI Key JJYKJUXBWFATTE-VIFPVBQESA-M
Synonym s---alpha-methoxy-alpha-trifluoromethyl phenylacetic acid, s-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid, --mosher's acid, --mtpa, unii-172hcj1iqv, 172hcj1iqv, 2s-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid, --alpha-methoxy-alpha-trifluoromethyl phenylacetic acid, s---mtpa, --a-methoxy-a-trifluoromethylphenylacetic acid
PubChem CID 6992788
IUPAC Name (2S)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid
SMILES CO[C@](C([O-])=O)(C1=CC=CC=C1)C(F)(F)F

Specifications

Melting Point 43°C to 45°C
Density 1.344
Boiling Point 105°C to 107°C (1 mmHg)
Flash Point >110°C (230°F)
Quantity 500 mg
Beilstein 3591561
Sensitivity Hygroscopic
Merck Index 14,6280
Solubility Information Readily soluble in hexane,ether,THF,CH2Cl2,benzene.
Optical Rotation −72° (c=2 in Methanol)
Formula Weight 234.18
Percent Purity 99%
Chemical Name or Material (S)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid
Show More Show Less

Safety and Handling

Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber 241-292-1
TSCA No
Recommended Storage Keep cold
SDS

RUO – Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.