(S)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride, 98+%

Description

CAS: 20445-33-4 | C10H8ClF3O2 | 252.617 g/mol

(S)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride is used in the preparation of natural products and pheromones. It is also employed as a derivatization enantiomeric purity reagent used for the determination of enantiomeric purity of alcohol and amines by gas chromatography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(S)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride is used in the preparation of natural products and pheromones. It is also employed as a derivatization enantiomeric purity reagent used for the determination of enantiomeric purity of alcohol and amines by gas chromatography.

Solubility
Slightly miscible with water.

Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents, strong acids and bases.

Specifications

Chemical Identifiers

• CAS: 20445-33-4
• Molecular Formula: C10H8ClF3O2
• Molecular Weight (g/mol): 252.617
• MDL Number: MFCD00067105
• InChI Key: PAORVUMOXXAMPL-SECBINFHSA-N
• Synonym: s-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride, +-mtpa-cl, unii-472va70ul4, 2s-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride, s-+-alpha-methoxy-alpha-trifluoromethylphenylacetyl chloride, s-+-a-methoxy-a-trifluoromethylphenylacetyl chloride, s-+-alpha-methoxy-alpha-trifluoromethylphenylacetylchloride, s-+-alpha-methoxy-alpha-trifluoromethyl phenylacetyl chloride, +-mtpa chloride, +-mosher's chloride
• PubChem CID: 2724611
• IUPAC Name: (2S)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride
• SMILES: COC(C1=CC=CC=C1)(C(=O)Cl)C(F)(F)F

• Density: 1.353
• Boiling Point: 213°C to 214°C
• Flash Point: 89°C (192°F)
• Refractive Index: 1.469
• Quantity: 50 mg
• UN Number: UN3265
• Beilstein: 3591564
• Sensitivity: Moisture sensitive
• Merck Index: 14,6280
• Solubility Information: Slightly miscible with water.
• Optical Rotation: +137° (c=6.4 in Carbon Tetrachloride)
• Formula Weight: 252.62
• Percent Purity: ≥98%
• Chemical Name or Material: (S)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride

Safety and Handling

Hazard Category	H227-H314-H335
Hazard Statement	GHS H Statement H314-H318-H227 Causes severe skin burns and eye damage. Causes serious eye damage. Combustible liquid.
Precautionary Statement	P210-P235-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
TSCA	No
Recommended Storage	Store at -20°C; Store under Nitrogen

SDS

RUO – Research Use Only