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Apexbio Technology LLC (S)-Flurbiprofen 51543-39-6 500mg
Supplier: Apexbio Technology LLC C5264500
(S)-Flurbiprofen (CAS 51543-39-6) is the pharmacologically active enantiomer of the 2-aryl propionic acid class of non-steroidal anti-inflammatory drugs (NSAIDs) It acts as a dual inhibitor of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with an IC50 of approximately 0 5 M against both isoforms in guinea pig whole blood assays In preclinical models topical administration of (S)-Flurbiprofen demonstrated significant analgesic and anti-inflammatory effects reducing inflammatory pain and edema in rat arthritis experiments Clinical studies have also supported its analgesic efficacy and safety in the management of osteoarthritis This compound is widely used in research focused on inflammation pain modulation and cyclooxygenase inhibition
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