(S)-(-)-Glycidol, 99+%, ee 99+%

Description

CAS: 60456-23-7 | C3H6O2 | 74.079 g/mol

(S)-(-)-Glycidol is employed in the synthesis of chiral (E)-allylic alcohol side-chains for introduction into prostacyclin and prostaglandin frameworks by cross-metathesis. Also used as a starting reagent to synthesize non-peptidic HIV protease inhibitors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(S)-(-)-Glycidol is employed in the synthesis of chiral (E)-allylic alcohol side-chains for introduction into prostacyclin and prostaglandin frameworks by cross-metathesis. Also used as a starting reagent to synthesize non-peptidic HIV protease inhibitors.

Solubility
Soluble in chloroform, DMSO and methanol.

Notes
Store in freezer at(-20°C). Keep container tightly closed. Store away from oxidizing agent.

Specifications

Chemical Identifiers

• CAS: 60456-23-7
• Molecular Formula: C3H6O2
• Molecular Weight (g/mol): 74.079
• MDL Number: MFCD00074874
• InChI Key: CTKINSOISVBQLD-VKHMYHEASA-N
• Synonym: s-glycidol, s-oxiranemethanol, s---glycidol, s-oxiran-2-ylmethanol, s---2,3-epoxy-1-propanol, 2s-oxiran-2-ylmethanol, s-+-glycidol, 2s-oxiran-2-yl methanol, oxiranemethanol, 2s
• PubChem CID: 6973630
• ChEBI: CHEBI:38690
• IUPAC Name: [(2S)-oxiran-2-yl]methanol
• SMILES: C1C(O1)CO

• Color: Yellow
• Density: 1.116 g/mL
• Boiling Point: 66°C to 67°C (19 mmHg)
• Flash Point: 66°C (151°F)
• Refractive Index: 1.433
• Quantity: 25 g
• UN Number: UN2810
• Beilstein: 79783
• Solubility Information: Soluble in chloroform,DMSO and methanol.
• Formula Weight: 74.08
• Percent Purity: ≥99%, ee
• Physical Form: Liquid
• Chemical Name or Material: (S)-(-)-Glycidol, ee ≥99%

Safety and Handling

Hazard Category	H227-H302+H312-H315-H319-H331-H335-H340-H350-H360
Hazard Statement	GHS H Statement H331-H350-H360-H341-H227-H302-H312-H315-H319-H335 Toxic if inhaled. May cause cancer. May damage fertility or the unborn child. Suspected of causing genetic defects. Combustible liquid. Harmful if swallowed. Harmful in contact with skin. Causes skin irritation.
Precautionary Statement	P201-P202-P210-P235-P261-P264b-P270-P271-P280i-P281-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P311-P312-P330-P332+P313-P362-P370+P378q-P501c
DOTInformation	Hazard Class: 6.1
RTECSNumber	RR0508100
TSCA	No
storageNote1	-30° to -10°C
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only