(S)-(+)-Ibuprofen, 99%, Thermo Scientific Chemicals

Catalog No.	Quantity	Packaging
AC333200010	1 g	Glass bottle
AC333200050	5 g	Glass bottle

Catalog No. AC333200010 Supplier Thermo Scientific Chemicals Supplier No. 333200010

Description

(S)-(+)-Ibuprofen, CAS # 51146-56-6, is the active enantomerof the non-steroidal anti-inflammatory drug, ibuprofen.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Ibuprofen is a nonsteroidal anti-inflammatory drug commonly used in its racemic form
• (S)-(+)-Ibuprofen is the active enantiomer of this drug that confers anti-inflammatory activity
• (S)-(+)-Ibuprofen inhibits prostaglandin synthesis and thus reduces inflammation and pain when ingested

Applications

• As the active enantiomer of ibuprofen, (S)-(+)-Ibuprofen is used in laboratory research for pharmacokinetic studies
• (S)-(+)-Ibuprofen may be used as an inhibitor of cycloogenase 1 and 2 and an agonist of PPARalpha and PPARgamma
• (S)-(+)-Ibuprofen may be used as material to study development of drug delivery systems

Specifications

Chemical Identifiers

• CAS: 51146-56-6
• Molecular Formula: C₁₃H₁₈O₂
• Molecular Weight (g/mol): 206.28
• MDL Number: MFCD00069289
• InChI Key: HEFNNWSXXWATRW-JTQLQIEISA-N
• Synonym: s-+-ibuprofen, dexibuprofen, s +-ibuprofen, s-2-4-isobutylphenyl propanoic acid, s-ibuprofen, d-ibuproten, s-+-2-4-isobutylphenyl propionic acid, s-+-4-isobutyl-alpha-methylphenylacetic acid, +-s-p-isobutylhydratropic acid, seractil
• PubChem CID: 39912
• ChEBI: CHEBI:43415
• IUPAC Name: (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid
• SMILES: CC(C)CC1=CC=C(C=C1)C(C)C(=O)O

• CAS Min %: 98.5
• CAS Max %: 100.0
• Melting Point: 49.0°C to 53.0°C
• Color: White
• Flash Point: 113°C
• Infrared Spectrum: Authentic
• Assay Percent Range: 98.5% min. (GC)
• Packaging: Glass bottle
• Quantity: 1 g
• Specific Rotation Condition: + 57.00 (20.00°C c=2,EtOH)
• Specific Rotation: + 57.00
• Solubility Information: Solubility in water: insoluble. Other solubilities: readily soluble in most organic solvents
• Formula Weight: 206.28
• Percent Purity: 99%
• Physical Form: Crystalline Powder or Crystals
• Chemical Name or Material: (S)-(+)-Ibuprofen, 99%

Safety and Handling

Hazard Category	GHS Signal Word: Warning
Hazard Statement	GHS H Statement Harmful if swallowed. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	GHS P Statement Use personal protective equipment as required. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
TSCA	TSCA

SDS

RUO – Research Use Only