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Medchemexpress LLC (S)-N-((S)-1-cyclohexyl-2-(3-morpholinopropanamido)ethyl)-3-(6-isopropylbenzo[d]thiazol-2-yl)-2-prop | 2245887-38-9 | 98.1% | 585.80 | C31H47N5O4S | 100MG
SDP

Supplier:  Medchemexpress LLC HY124602100MG

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DI-591 is a cell-permeable, high-affinity small-molecule inhibitor of the DCN1-UBC12 interaction. It binds human DCN1 and DCN2 with low nanomolar affinity (Ki ≈ 10-12 nM) and selectively inhibits neddylation of cullin 3, making it a useful chemical probe for studying cullin 3-dependent CRL biology and related cellular processes.

  • High affinity, low nanomolar binding to DCN1 and DCN2.
  • Cell-permeable small-molecule probe suitable for cellular assays.
  • Selectively inhibits neddylation of cullin 3 with minimal effect on other cullins.
  • Available as powder and as a 10 mM solution in DMSO for convenience.
  • High purity for research use and stability under recommended storage conditions.

Catalog No. 50-002-36787


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