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Medchemexpress LLC (S,R)-GSK321 | 1816272-18-0 | 98.6% | 100 MG
SDP

Catalog No. 5000338670
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(S,R)-GSK321 is the (S,R)-enantiomer of GSK321. It is a potent, selective mutant IDH1 inhibitor with IC50 values for R132G, R132C, R132H, and WT IDH1, and exhibits >100-fold selectivity over IDH2. (S,R)-GSK321 induces a decrease in intracellular 2-HG, abrogation of the myeloid differentiation block, and induction of granulocytic differentiation. It can be used for research of acute myeloid leukemia (AML) and other cancers.

  • Potent, selective mutant IDH1 inhibitor
  • Induces a decrease in intracellular 2-HG
  • Abrogation of myeloid differentiation block
  • Induction of granulocytic differentiation
  • Useful in research for acute myeloid leukemia (AML) and other cancers
  • Store powder at -20°C for 3 years or 4°C for 2 years
  • Store in solvent at -80°C for 6 months or -20°C for 1 month

Catalog No. 50-003-38670 Supplier Medchemexpress LLC Supplier No. HY128888B100MG
May include imposed supplier surcharges.
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(S,R)-GSK321 is the (S,R)-enantiomer of GSK321. It is a potent, selective mutant IDH1 inhibitor with IC50 values for R132G, R132C, R132H, and WT IDH1, and exhibits >100-fold selectivity over IDH2. (S,R)-GSK321 induces a decrease in intracellular 2-HG, abrogation of the myeloid differentiation block, and induction of granulocytic differentiation. It can be used for research of acute myeloid leukemia (AML) and other cancers.

  • Potent, selective mutant IDH1 inhibitor
  • Induces a decrease in intracellular 2-HG
  • Abrogation of myeloid differentiation block
  • Induction of granulocytic differentiation
  • Useful in research for acute myeloid leukemia (AML) and other cancers
  • Store powder at -20°C for 3 years or 4°C for 2 years
  • Store in solvent at -80°C for 6 months or -20°C for 1 month

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