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Medchemexpress LLC (S,R)-GSK321 | 1816272-18-0 | 98.6% | 501.55 g/mol | C28H28FN5O3 | 5 MG
Supplier: Medchemexpress LLC HY128888B5MG
(S,R)-GSK321 is the (S,R)-enantiomer of GSK321, a potent and selective mutant isocitrate dehydrogenase 1 (IDH1) inhibitor used as a research tool to study IDH1-driven oncogenic metabolism and differentiation. It reduces intracellular 2-hydroxyglutarate (2-HG) levels and promotes granulocytic differentiation in leukemic cells, supporting studies in acute myeloid leukemia and related cancers.
- Potent mutant IDH1 inhibitor with nanomolar activity.
- Reduces intracellular 2-hydroxyglutarate (2-HG) levels.
- Promotes granulocytic differentiation in leukemic cells.
- High purity suitable for research applications (98.6%).
- Molecular weight 501.55 g/mol; molecular formula C28H28FN5O3.
- Available in small research pack sizes, including 5 mg.
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