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Cayman Chemical S-SulfocysteIn 10mg
Supplier: Cayman Chemical 3455910 MG
An NMDA receptor agonist; selective for the NMDA receptor over the AMPA receptor in radioligand binding assays (EC50s = 8.2 and 59 µM, respectively); cytotoxic to primary mouse neuronal cells at 200 µM; induces calcium influx and activates calpain-dependent degradation of gephyrin at 100 µM; increases swimming and seizure-like movements, indicating neurodegeneration, in zebrafish larvae at 2 mM three days post-fertilization; urinary and plasma levels of S-sulfocysteine are increased in patients with MoCD
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