Invitrogen™ Human S100A10 Recombinant Protein

Catalog No.	Quantity
PIRP75716	100 μg

Catalog No. PIRP75716 Supplier Invitrogen™ Supplier No. RP75716

Description

Recombinant Protein

This product contains purified recombinant human S100A10 protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.

The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.

Specifications

• Accession Number: P60903
• Concentration: 0.10 mg/mL
• For Use With (Application): Control, Western Blot
• Formulation: PBS with 50% glycerol and no preservative
• Gene ID (Entrez): 6281
• Molecular Weight (g/mol): 15.3 kDa
• Name: Human S100A10
• Quantity: 100 μg
• Source: E. Coli
• Immunogen: N/A
• Regulatory Status: RUO
• Gene Alias: 42 C; AA409961; AL024248; Annexin II; annexin II ligand; annexin II ligand, calpactin I, light polypeptide; annexin II tetramer (AIIt) p11 subunit; AN x 2 L; AN x 2 LG; Ca[1 ]; CAL12; Cal1l; calcium binding protein A11 (calgizzarin); calpactin I light chain; Calpactin-1 light chain; cellular ligand of annexin II; CLP11; GP11; MGC111133; MGC133268; Nerve growth factor-induced protein 42 C; OTTHUMP00000015270; P PRSS26; p10; p10 protein; P11; p11 subunit; Protein S100 A10; Protein S100-A10; S100 calcium binding protein A10; S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S100 calcium binding protein A10 (calgizzarin); S100 calcium binding protein A10 (calpactin); S100 calcium-binding protein A10; S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S-100 related protein, clone 42 C; S100a10
• Common Name: S100A10
• Gene Symbol: S100A10
• Conjugate: Unconjugated
• Species: E. coli
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Amino acids Met1-Lys97 containing an N-terminal His-tag
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Protein Subtype: Recombinant
• Purity or Quality Grade: >95%, by SDS-PAGE under reducing conditions

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov