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Eurofins Discoverx Ready-to-Assay S1P5 Lysophospholipid Receptor Frozen Cells, 2 Vials of Cells. (HTS193RTA)

Supplier:  Eurofins Discoverx HTS193RTA

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The Ready-to-Assay S1P5 Lysophospholipid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. S1P) based activation of S1PR5 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses S1PR5 alongside exogenous levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of S1PR5, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.

Catalog No. 50-200-6045


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