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Medchemexpress LLC S65487 hydrochloride | 1644543-95-2 | 99.7% | 753.72 g/mol | C41H42Cl2N6O4 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY138697B5MG

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S65487 hydrochloride is a research-stage small molecule that selectively inhibits BCL-2 and acts as a proagent of S55746. It induces apoptosis in hematological cancer cell lines and retains activity against certain BCL-2 mutations (for example, G101V and D103Y), while showing low affinity for MCL-1, BFL-1, and BCL-XL.

  • Selective BCL-2 inhibition observed in cell-based assays.
  • Active against clinically relevant BCL-2 mutations.
  • Induces apoptosis and reduces proliferation in hematological cancer models.
  • Suitable for preclinical biochemical and cellular research.
  • High reported purity for consistent experimental results.

Catalog No. 50-002-21186


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