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Medchemexpress LLC S65487 (VOB560) | 1644600-79-2 | 99.9% | 717.26 | 50 MG
Supplier: Medchemexpress LLC HY13869750MG
S65487 (VOB560) is a potent and selective BCL-2 inhibitor and a proagent of S55746. It is active against BCL-2 mutations such as G101V and D103Y, and exhibits poor affinity with MCL-1, BFL-1, and BCL-XL. This compound induces apoptosis and demonstrates anticancer activities.
- Potent and selective BCL-2 inhibitor
- Active against BCL-2 mutations (G101V and D103Y)
- Induces apoptosis and inhibits cell proliferation in various hematological cancer cell lines
- Demonstrates anticancer activities in vivo, causing complete tumor regression
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