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Medchemexpress LLC Sabutoclax | 1228108-65-3 | C42H40N2O8 | 5 MG
Supplier: Medchemexpress LLC HY151915MG
Sabutoclax is a potent and effective inhibitor of the Bcl-2 Family, targeting Bcl-2, Bcl-XL, Mcl-1, and Bfl-1. It enhances the expression of pro-apoptotic proteins such as Bax, Bim, PUMA, and survivin, playing a role in inducing cell apoptosis and inhibiting cancer cell growth.
- Potent and effective Bcl-2 family inhibitor.
- Increases Bax, Bim, PUMA, and survivin expression.
- Inhibits cell growth in human prostate and lung cancer cell lines.
- Induces cell apoptosis in human diffuse large B-cell lymphoma cells.
- Upregulates pro-apoptotic proteins in chemoresistant cells.
- Reduces tumor growth in animal models.
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