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Apexbio Technology LLC Safinamide Mesylate 202825-46-5 50mg
Supplier: Apexbio Technology LLC A436850
Safinamide Mesylate (CAS 202825-46-5) is the mesylate salt form of safinamide a selective and reversible inhibitor of monoamine oxidase B (MAO-B) Safinamide exhibits an IC50 of 98 nM for MAO-B inhibition leading to enhanced dopaminergic transmission by reducing dopamine degradation In addition to MAO-B inhibition safinamide modulates sodium and calcium channels (IC50 8 2 M and 31 5 M respectively) and suppresses glutamate release ( 56 4 M) contributing to its anticonvulsant properties Research applications include the study of Parkinson s disease mechanisms and the investigation of dopaminergic and glutamatergic modulation
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