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Medchemexpress LLC Saikogenin A | 5092-09-1 | 1 MG
SDP

Catalog No. 5000417972
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Saikogenin A, extracted from a Chinese herbal plant called Tsai-Fu, is a dipeptidyl peptidase-IV (DPP-IV) inhibitor. It is for research use only and not sold to patients.

  • Exhibits an inhibitory effect on the enzyme DPP-IV, with 47.6% inhibition at a concentration of 20 μg/mL.
  • DPP-IV is a non-classical serine aminopeptidase that removes Xaa-Pro dipeptide from the N-terminus of polypeptides and proteins.
  • Acts as an anti-inflammatory drug.
  • Anti-inflammatory effects are attributed to an increase in corticosterone and a direct impact on the inflammation process.
  • Found to be less effective in reducing carrageenin-induced edema in adrenalectomized rats compared to normal rats.
  • Shows low cytotoxicity against human cells (A549, Bcap37, Hep 3B2, HepG2, MCF7) with IC50 > 80 μM.

Catalog No. 50-004-17972 Supplier Medchemexpress LLC Supplier No. HYN65841MG
May include imposed supplier surcharges.
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Saikogenin A, extracted from a Chinese herbal plant called Tsai-Fu, is a dipeptidyl peptidase-IV (DPP-IV) inhibitor. It is for research use only and not sold to patients.

  • Exhibits an inhibitory effect on the enzyme DPP-IV, with 47.6% inhibition at a concentration of 20 μg/mL.
  • DPP-IV is a non-classical serine aminopeptidase that removes Xaa-Pro dipeptide from the N-terminus of polypeptides and proteins.
  • Acts as an anti-inflammatory drug.
  • Anti-inflammatory effects are attributed to an increase in corticosterone and a direct impact on the inflammation process.
  • Found to be less effective in reducing carrageenin-induced edema in adrenalectomized rats compared to normal rats.
  • Shows low cytotoxicity against human cells (A549, Bcap37, Hep 3B2, HepG2, MCF7) with IC50 > 80 μM.

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