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Cayman Chemical SaIkosaponIn Dhydrate 50mg
Supplier: Cayman Chemical 3315650 MG
A triterpene saponin with diverse biological activities; inhibits the proliferation of, and induces apoptosis in, SW1736, ARO, and 8305C anaplastic thyroid cancer cells from 5-20 µM; reduces tumor weight and volume in an ARO mouse xenograft model at 5, 10, and 20 mg/kg; reverses reductions in gut microbial diversity, reduces colonic inflammatory cell infiltration, mucosal thickening, and goblet cell depletion, and increases colon length in a mouse model of DSS-induced ulcerative colitis; has antidepressant-like activity and inhibits LPS-induced hippocampal microglial activation in mice at 1 mg/kg
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