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TARGETMOL CHEMICALS INC SAMURACICLIB HYDROCHLORI 5MG

Supplier: TARGETMOL CHEMICALS INC T108985MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Samuraciclib hydrochloride (ICEC0942 hydrochloride) is a potent selective ATP competitive and oral active CDK7 inhibitor with IC50 of 41 nM. The selectivity of Samuraciclib hydrochloride is 45- 15- 230- and 30-fold higher than CDK1 CDK2 (IC50 is 578 nM) CDK5 and CDK9 respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 uM. Samuraciclib hydrochloride has anti-tumor effects. purity: 99%
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