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Medchemexpress LLC Sapropterin dihydrochloride | 69056-38-8 | 99.8% | C9H17Cl2N5O3 | 25 MG
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Supplier:  Medchemexpress LLC 25MGHYA0124AR

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Sapropterin dihydrochloride is an orally active phenylalanine hydroxylase (PAH) cofactor. It is effective in reducing blood phenylalanine concentrations and can be used in the study of phenylketonuria (PKU). Additionally, it has been shown to aggravate experimental autoimmune encephalomyelitis (EAE).

  • Enhances residual phenylalanine hydroxylase activity to increase phenylalanine oxidation.
  • Aggravates experimental autoimmune encephalomyelitis (EAE) in SJL/J mice.
  • Increases clinical EAE scores and elevates plasma long-chain ceramide levels.
  • Reduces linolenic acid levels and increases spinal cord T-cell infiltration.

Catalog No. 50-003-58894


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