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Medchemexpress LLC SAR405 | 1523406-39-4 | MFCD28411361 | >98.0% | 443.9 | C19H21ClF3N5O2 | 2MG
SDP

Supplier:  Medchemexpress LLC HY124812MG

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SAR405 is a research-grade small-molecule inhibitor of the class III phosphatidylinositol 3-kinase (Vps34/PIK3C3). It potently inhibits Vps34 activity (reported IC50 = 1.2 nM; Kd = 1.5 nM) and is used in cellular and biochemical studies to block autophagosome formation and alter vesicle trafficking. Supplied as a high-purity solid suitable for laboratory research.

  • Potent Vps34 inhibitor (IC50 = 1.2 nM).
  • Blocks autophagosome formation and inhibits autophagy.
  • Useful for cellular and biochemical studies of vesicle trafficking.
  • Supplied as a high-purity solid or powder for research use.
  • Available in small, research-scale quantities suitable for assay development.
  • Characterized in peer-reviewed publications for target engagement.

Catalog No. 50-202-8885


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