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Medchemexpress LLC SAR407899 hydrochloride | 923262-96-8 | MFCD20485429 | 99.1% | 280.75 g/mol | C14H17ClN2O2 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY1568710MG

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SAR407899 hydrochloride is a selective, potent, ATP-competitive inhibitor of Rho-associated kinases (ROCK), supplied as a high-purity solid for preclinical biochemical and cellular research. It is used to probe ROCK-mediated signaling, vascular tone, and smooth muscle responses in vitro and in vivo.

  • Selective ATP-competitive ROCK inhibitor with ROCK-2 IC50 ≈135 nM.
  • Demonstrates Ki values of 36 nM (human) and 41 nM (rat).
  • High purity (99.1%) suitable for research applications.
  • Solid, light yellow to khaki appearance; stable when stored sealed at 4°C.
  • Applicable to studies of vascular tone, smooth muscle relaxation, and ROCK signaling pathways.

Catalog No. 50-002-87998


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