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Medchemexpress LLC Sardomozide dihydrochloride | 138794-73-7 | 99.73% | 303.19 | 100 MG
Supplier: Medchemexpress LLC HY13746B100MG
Sardomozide dihydrochloride is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM. It is for research use only. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When CHO/664 cells are grown in the presence of Sardomozide and treated with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to parental CHO cells.
- S-adenosylmethionine decarboxylase (SAMDC) inhibitor
- IC50 of 5 nM
- Reduces intracellular SAMDC activity to 10% of control after 48 h treatment with 3 μM
- Prevents vacuole formation in CHO/664 cells when treated with DENSPM
- Inhibits growth of CHO/664 cells
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