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Cayman Chemical SardomozIdehydrochlorIde 10mg
Supplier: Cayman Chemical 3490110 MG
An inhibitor of SAMDC (IC50 = 0.005 µM for the rat liver enzyme); selective for SAMDC over DAO (IC50 = 18 µM for the rat small intestine enzyme); inhibits proliferation of T24 cells (IC50 = 0.71 µM); decreases intracellular levels of spermidine and spermine and increases intracellular putrescine levels in L1210 cells at 3 µM; inhibits HIV-1 replication in PM1 cells at 0.2 and 0.4 µM; reduces tumor growth in a SK-MEL-24 melanoma mouse xenograft model at 0.5 and 5 mg/kg
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