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Medchemexpress LLC Saroglitazar magnesium | 1639792-20-3 | 98.0% | 901.42 | 1 MG
Supplier: Medchemexpress LLC HY19937A1MG
Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity, having EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. It is for research use only.
- Pparα agonist (ec50: 0.65 pm in hepg2 cells)
- Moderate pparγ activity (ec50: 3 nm in hepg2 cells)
- Causes dose-dependent reductions in serum triglycerides, free fatty acids, and glucose in db/db mice.
- Shown efficacy in lowering triglycerides in wistar rats and marmosets.
- Appears to have good potential as a therapeutic agent for dyslipidemia and diabetes.
- Appearance: solid
- Color: off-white to light yellow
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