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Apexbio Technology LLC Sarpogrelate hydrochloride 135159-51-2 10mM (in 1mL DMSO)
SDP

Catalog No. 5000094691
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Sarpogrelate hydrochloride (CAS 135159-51-2) is a selective antagonist of the 5-HT2A receptor exhibiting a binding affinity (Ki) of 8 39 nM comparable to ritanserin By inhibiting 5-HT2A receptor-mediated pathways sarpogrelate suppresses platelet aggregation thrombus formation and vascular smooth muscle cell proliferation In vitro its primary metabolite (M-1) blocks 5-HT-induced responses at the 5-HT2A receptor with minimal stereoselective difference Clinically oral administration of sarpogrelate in patients with peripheral arterial disease significantly enhances forearm and leg blood flow responses to reactive hyperemia indicating improved vascular function Sarpogrelate is employed in research on platelet function thrombosis and vascular disorders

Catalog No. 50-000-94691 Supplier Apexbio Technology LLC Supplier No. B34945.1
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Sarpogrelate hydrochloride (CAS 135159-51-2) is a selective antagonist of the 5-HT2A receptor exhibiting a binding affinity (Ki) of 8 39 nM comparable to ritanserin By inhibiting 5-HT2A receptor-mediated pathways sarpogrelate suppresses platelet aggregation thrombus formation and vascular smooth muscle cell proliferation In vitro its primary metabolite (M-1) blocks 5-HT-induced responses at the 5-HT2A receptor with minimal stereoselective difference Clinically oral administration of sarpogrelate in patients with peripheral arterial disease significantly enhances forearm and leg blood flow responses to reactive hyperemia indicating improved vascular function Sarpogrelate is employed in research on platelet function thrombosis and vascular disorders

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