Cayman Chemical SarpogrelAThydrochLRIde 100mg

Supplier:  Cayman Chemical 24194100 MG

A selective 5-HT2 receptor antagonist (Kis = 3.02, 269, and 37.2 nM, respectively, for human recombinant 5-HT2A, 5-HT2B, and 5-HT2C expressed in CHO-K1 cells); selective for 5-HT2 (Ki = 70.8 nM) over 5-HT1 (Ki = >26,000 nM), α1-, α2-, and β-adrenergic (Kis = 640-123,800 nM), and muscarinic receptors (Ki = >40,000 nM); inhibits aggregation of rat whole blood induced by collagen, 5-HT with collagen, and 5-HT with ADP (IC50s = 57.7, 0.56, and 22.7 μM, respectively); inhibits HFFD-induced leukocyte-endothelial interactions in the femoral artery in mice (5 mg/kg per day); decreases ventricular hypertrophy and infarct size in a rat model of myocardial infarction (5 mg/kg per day)

Catalog No. 50-293-4677