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AdipoGen SARS-CoV-2 S1 RBDFcB16171
SDP

Supplier:  AdipoGen AG40B0209C050

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Protein. Receptor-binding domain RBD of SARS-CoV-2 Spike protein S1 aa 319-541 containing the mutations L452R & E484Q is fused to the N-terminus of the Fc region of human IgG1. Binds to anti-SARS-CoV-2 Spike RBD antibodies in serum or plasma. Binds to human ACE2. Lyophilized. Contains PBS. Produced in HEK 293 cells. SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is 96.2% identical at the genome level to the bat coronavirus BatCoV RaTG133, suggesting it had originated in bats. The coronaviral genome encodes four major structural proteins the Spike S protein, Nucleocapsid N protein, Membrane/Matrix M protein and the Envelope E protein. The SARS Envelope E protein contains a short palindromic transmembrane helical hairpin that seems to deform lipid bilayers, which may explain its role in viral budding and virion envelope morphogenesis. The SARS Membrane/Matrix M protein is one of the major structural viral proteins.

Catalog No. 50-256-2873


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