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AdipoGen SARS-CoV-2 S1 RBDHisB1351
Supplier: AdipoGen AG40B0206C050
Recombinant Protein. Receptor-binding domain RBD of SARS-CoV-2 Spike protein S1 aa 319-541 containing the mutations K417N, E484K, N501Y is fused at the C-terminus to a His-tag. Source HEK 293 cells. Binds to anti-SARS-CoV-2 Spike RBD antibodies in serum or plasma. Binds to human ACE2. Endotoxin <0.01EU/µg purified protein LAL test.. SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is 96.2% identical at the genome level to the bat coronavirus BatCoV RaTG133, suggesting it had originated in bats. The coronaviral genome encodes four major structural proteins the Spike S protein, Nucleocapsid N protein, Membrane/Matrix M protein and the Envelope E protein. The SARS Envelope E protein contains a short palindromic transmembrane helical hairpin that seems to deform lipid bilayers, which may explain its role in viral budding and virion envelope morphogenesis. The SARS Membrane/Matrix M protein is one of the major structural viral proteins.
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