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ACROBiosystems ACROBiosystems SARS-CoV-2 S2 protein (T1027I, V1176F), His Tag
Supplier: ACROBiosystems S2NC52HE1MG
Recombinant Protein;1MG;SARS-CoV-2 S2 protein (T1027I, V1176F), His Tag (S2N-C52He) is expressed from human 293 cells (HEK293). It contains AA Ser 686 - Pro 1213 (Accession # QHD43416.1). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P/ A892P/ A899P/ A942P/ K986P/ V987P) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein. The T1027I/ V1176F mutations were identified in the SARS-CoV-2 variant (known as P.1) which emerged in Brazil.;This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 59.9 kDa. The protein migrates as 70-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.;Immobilized SARS-CoV-2 S2 protein (T1027I, V1176F), His Tag (Cat. No. S2N-C52He) at 1 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Spike S2 protein Antibody, Human IgG4 (Cat. No. S2N-S86) with a linear ran
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