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AdipoGen SARS-CoV-2 Spike D614G His
SDP

Supplier:  AdipoGen AG40B6003C050

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Recombinant protein. Full-length soluble SARS-CoV-2 Spike protein aa 16-1213 including a foldon trimerization motif, mutated Furin recognition site R682S, R685S and two stabilizing mutations K986P and V987P is fused at the C-terminus to a His-tag. Binds to the human SARS-CoV-2 receptor ACE2. Binds to anti-SARS-CoV-2 Spike antibodies in serum or plasma. Source HEK 293 cells. Lyophilized. Contains PBS and 20% glycerol. Purity >90% SDS-PAGE. SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is 96.2% identical at the genome level to the bat coronavirus BatCoV RaTG133, suggesting it had originated in bats. The original Wuhan strain of the virus has become quickly replaced by its more transmissible variant, mainly determined by a single amino acid point mutation D614G. The coronaviral genome encodes four major structural proteins the Spike S protein, Nucleocapsid N protein, Membrane/Matrix M protein and the Envelope E protein.

Catalog No. 50-256-2804


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