Invitrogen™ SARS-CoV-2 Spike Protein (RBD) (aa330-524), His Tag Recombinant Protein

Catalog No.	Quantity
PIRP87674	100 μg
PIRP87683	200 μg
PIRP87684	1 mg

Catalog No. PIRP87674 Supplier Invitrogen™ Supplier No. RP87674

Description

Recombinant Protein

RP-87674 has been tested in indirect ELISA. Reconstitution: It is recommend that the vial be centrifuged briefly (∽30 seconds) before opening the tube in order to bring the contents to the bottom. Then, reconstitute the protein with 400 μL of deionized sterile water to obtain a final concentration of 0.5 mg/mL. Let the tube sit on ice for ∽30 minutes with gentle pipetting periodically.

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.

Specifications

• Concentration: Conc. Not Determined
• For Use With (Application): Control, ELISA Standard, Binding Assay
• Formulation: PBS with no preservative
• Molecular Weight (g/mol): 27 kDa
• Name: SARS-CoV-2 Spike Protein (RBD) (aa330-524), His Tag
• Purification Method: Purified
• Quantity: 100 μg
• Source: E. coli
• Storage Requirements: -20°C or -80°C if preferred
• Regulatory Status: RUO
• Gene Alias: Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
• Common Name: SARS-CoV-2 Spike Protein RBD
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: SARS-CoV-2 Spike Protein (s-RBD) contains amino acids 330-524 of the SARS-CoV-2 Spike protein with a His-tag
• Content And Storage: -20°Cor to +80°C if preferred
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: >95% by SDS-PAGE under reducing conditions