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Cayman Chemical SARSCoV2 B 1 1 7 SpIke Reag

Supplier: Cayman Chemical 502181100 DTN

An imidazoline receptor agonist selectively binds to imidazoline I1 and -I2 receptors over a2-ARs (IC50s 0.034 0.026 and 15 UM respectively) reduces complete Freund’s adjuvant-induced thermal and mechanical hyperalgesia in rats at 10 or 17.8 mg/kg decreases the latency to seizure onset and increases the percentage of animals with grade V seizures to a greater extent in female than male mice reverses cognitive deficits in the 5XFAD transgenic mouse model of Alzheimer’s disease at 5 mg/kg
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