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Enzo Life Sciences Sauchinone (5mg). CAS: 177931-17-8
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Supplier:  Enzo Life Sciences ALX350116M005

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Diastereomeric lignan with cytoprotective and antioxidant activities in cultured hepatocytes. Inhibitor of LPS-inducible iNOS (NOS II), TNF-α and COX-2 expression in macrophages through suppression of IκBα phosphorylation and p65 nuclear translocation and of C/EBP and/or AP-1 activation, which may have constitutive anti-inflammatory effects. Suppressor of NF-κB by inhibiting transactivation activity of the RelA subunit. Inhibits staurosporine (ALX-380-014)-induced apoptosis. Inhibits RANKL-induced osteoclastogenesis by reducing ROS generation. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO or chloroform. Long Term Storage: Ambient.

Catalog No. 50-200-8739


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