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Medchemexpress LLC Saxagliptin (hydrochloride) | 709031-78-7 | 99.7% | 351.87 | 25 MG
Supplier: Medchemexpress LLC 25MGHY16448
Saxagliptin hydrochloride is a potent, selective, reversible, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor with a Ki of 0.6-1.3 nM. This compound has potential for research into type 2 diabetes mellitus.
- Potent inhibitor of dipeptidyl peptidase-4 (DPP-4).
- Selective and reversible action.
- Orally active compound.
- Increases β-cell proliferation.
- Increases p-AKT and active β-catenin protein levels.
- Increases c-myc and cyclin D1 protein expression.
- Prevents degradation of glucagon-like peptide-1.
- Increases secretion of insulin.
- Decreases secretion of glucagon.
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