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Medchemexpress LLC Saxagliptin (hydrochloride) | 709031-78-7 | 99.71% | 351.87 | 1 ML
SDP

Catalog No. 5000391569
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Saxagliptin hydrochloride is a potent, selective, reversible, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. It has the potential for research in type 2 diabetes mellitus.

  • It acts by preventing the degradation of glucagon-like peptide-1, which increases insulin secretion and decreases glucagon secretion.
  • Studies have shown that saxagliptin can induce β-cell proliferation.
  • It has been observed to increase p-AKT and active β-catenin protein levels, alongside increased c-myc and cyclin D1 protein expression.
  • It dose-dependently inhibits plasma DPP-4 activity.

Catalog No. 50-003-91569 Supplier Medchemexpress LLC Supplier No. HY1644810MM/1ML
May include imposed supplier surcharges.
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Saxagliptin hydrochloride is a potent, selective, reversible, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. It has the potential for research in type 2 diabetes mellitus.

  • It acts by preventing the degradation of glucagon-like peptide-1, which increases insulin secretion and decreases glucagon secretion.
  • Studies have shown that saxagliptin can induce β-cell proliferation.
  • It has been observed to increase p-AKT and active β-catenin protein levels, alongside increased c-myc and cyclin D1 protein expression.
  • It dose-dependently inhibits plasma DPP-4 activity.

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