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Cayman Chemical SB-200646hydrochlorIde 10mg

Supplier: Cayman Chemical 3097310 MG
A dual antagonist of 5-HT2C (Ki = 125 nM in isolated rat cortex) and 5-HT2B receptors (pA2 = 7.5 in rat stomach fundus preparations); selective for 5-HT2C and 5-HT2B over 5-HT1A, 5-HT2A, 5-HT1D, 5-HT3, benzodiazepine, GABAA, α1-, α2A-, α2B-, β1-, and β2-adrenergic, dopamine D1 and D2, and histamine H1 receptors (Kis = >10 µM for all); reverses mCPP-induced hypophagia and decreases in social interaction time in rats at 20 and 40 mg/kg
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