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Medchemexpress LLC SB 452533 | 459429-39-1 | 99.1% | 376.29 | 1 ML
Supplier: Medchemexpress LLC HY10845850MG
SB 452533 is a potent and selective TRPV1 antagonist with a pKb of 7.8. It is for research use only and not sold to patients.
- Potent antagonist at the cloned recombinant rat TRPV1 receptor in HEK293 cells.
- Reduces phosphorylation of CAMKK2 and AMPK.
- Abolishes the effects of small dose Capsaicin in reducing Bleomycin-induced pulmonary fibrosis in mice.
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