Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000064370

Apexbio Technology LLC SB-505124 hydrochloride 356559-13-2 10mM (in 1mL DMSO)
SDP

Supplier:  Apexbio Technology LLC A37995.1

Encompass_Preferred

SB-505124 hydrochloride (CAS 356559-13-2) is a potent selective inhibitor targeting transforming growth factor-beta (TGF ) receptors ALK4 and ALK5 SB-505124 functions by reversibly competing with ATP binding exhibiting IC50 values of 129 nM for ALK4 and 47 nM for ALK5 By blocking these receptor kinases the compound effectively inhibits downstream signaling events such as Smad2/3 phosphorylation and expression of TGF -regulated genes ( -SMA and CTGF) Research demonstrates its applicability in fibrotic disease models including glaucoma filtration surgery by preventing fibroblast activation and extending filtration bleb lifespan in vivo

Catalog No. 50-000-64370


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.