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Cayman Chemical SB-505124hydrochlorIde 10mg
SDP

Supplier:  Cayman Chemical 4205610 MG

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An ALK5 and ALK4 inhibitor (IC50s = 47 and 129 nM, respectively); selective for ALK5 and ALK4 over a panel of 27 kinases at 10 µM; inhibits ALK7-induced increases in phosphorylated SMAD2 levels in COS-1 cells overexpressing ALK7 at 5 µM; inhibits TGF-β-induced but not TNF-α-induced apoptosis in Fao cells at 1 µM; decreases IOP and subconjunctival immune cell infiltration in a rabbit model of trabeculectomy at 5 mg/eye

Catalog No. 50-294-5289


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