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Medchemexpress LLC SB-612111 hydrochloride | 371980-98-2 | 99.64% | 454.86 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY18618A5MG

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SB-612111 hydrochloride is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). It exhibits selectivity for μ-, κ- and δ-receptors with Ki values of 57.6 nM, 160.5 nM, and 2109 nM, respectively. It effectively antagonizes the pronociceptive action of Nociceptin in an acute pain model.

  • ORL-1 inhibitor
  • Effectively antagonizes the pronociceptive action of nociceptin in an acute pain model
  • Appearance: Solid
  • Color: White to off-white

Catalog No. 50-003-88010


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