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Medchemexpress LLC SB-612111 hydrochloride | 99.6% | 454.86 | 1 ML

Supplier: Medchemexpress LLC HY18618A10MM/1ML
SB-612111 hydrochloride is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist with high affinity for hORL-1 (Ki = 0.33 nM). It demonstrates selectivity for μ-, κ-, and δ-receptors. This compound effectively antagonizes the pronociceptive action of Nociceptin in an acute pain model.
- Potent ORL-1 antagonist with high affinity.
- Exhibits selectivity for μ-, κ-, and δ-receptors.
- Effectively antagonizes pronociceptive action of Nociceptin.
- Demonstrates antihyperalgesic effects in animal models.
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