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Medchemexpress LLC SB-616234-A | 908601-49-0 | 99.4% | 574.11 | 1 MG
SDP

Catalog No. 5000384661
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SB-616234-A is a selective and orally bioavailable 5-HT1B receptor antagonist, demonstrating anxiolytic and antidepressant activity. It exhibits high affinity and selectivity for 5-HT1B receptors, acting as a potent antagonist without agonist activity.

  • Acts as a selective and orally bioavailable 5-HT1B receptor antagonist.
  • Demonstrates anxiolytic and antidepressant activity.
  • Exhibits high affinity for human 5-HT1B receptors.
  • Shows over 100-fold selectivity for most molecular targets.
  • Functions as a high-affinity antagonist without agonist activity.
  • Potentiates electrically stimulated 5-HT release.
  • Reverses SKF-99101H-induced hypothermia in guinea pigs.
  • Produces dose-related anxiolytic effects in animal models.

Catalog No. 50-003-84661 Supplier Medchemexpress LLC Supplier No. HY194771MG
May include imposed supplier surcharges.
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SB-616234-A is a selective and orally bioavailable 5-HT1B receptor antagonist, demonstrating anxiolytic and antidepressant activity. It exhibits high affinity and selectivity for 5-HT1B receptors, acting as a potent antagonist without agonist activity.

  • Acts as a selective and orally bioavailable 5-HT1B receptor antagonist.
  • Demonstrates anxiolytic and antidepressant activity.
  • Exhibits high affinity for human 5-HT1B receptors.
  • Shows over 100-fold selectivity for most molecular targets.
  • Functions as a high-affinity antagonist without agonist activity.
  • Potentiates electrically stimulated 5-HT release.
  • Reverses SKF-99101H-induced hypothermia in guinea pigs.
  • Produces dose-related anxiolytic effects in animal models.

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