Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC SB-616234-A | 908601-49-0 | 99.4% | 574.11 | 50 MG
Supplier: Medchemexpress LLC HY1947750MG
SB-616234-A is a selective and orally bioavailable 5-HT1B receptor antagonist, which demonstrates anxiolytic and antidepressant activity. It is intended for research use only.
- Selective 5-HT1B receptor antagonist
- Orally bioavailable
- Anxiolytic activity
- Antidepressant activity
- High affinity for human 5-HT1B receptors
- Over 100-fold selective for most molecular targets, except h5-HT1D receptors
- Acts as a high affinity antagonist in [35S]-GTPγS binding studies
- Potentiates electrically stimulated [3H]-5-HT release
- Reverses SKF-99101H-induced hypothermia
- Produces dose-related anxiolytic effects in maternal separation-induced vocalisation models
- Causes a dose-dependent inhibition of ex vivo [3H]-GR125743 binding to rat striatal 5-HT1B receptors
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?