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Medchemexpress LLC SB-747651A dihydrochloride | 1781882-72-1 | 99.1% | 415.32 | 100 MG
SDP

Catalog No. 5000343599
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SB-747651A dihydrochloride is an ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor. It can be used for inflammation research, and also inhibits PRK2, RSK1, p70S6K, and ROCK-II.

  • Inhibits MSK1 with an IC50 of 11 nM.
  • Affects CXCL2-induced intraluminal crawling of neutrophils.
  • Thwarts intraluminal crawling of adherent neutrophils to optimal sites of emigration.
  • Significantly increases transmigration time and detachment time.
  • Inhibits the migration speed of extravascular chemotaxing neutrophils.

Catalog No. 50-003-43599 Supplier Medchemexpress LLC Supplier No. HY11031310MG
May include imposed supplier surcharges.
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SB-747651A dihydrochloride is an ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor. It can be used for inflammation research, and also inhibits PRK2, RSK1, p70S6K, and ROCK-II.

  • Inhibits MSK1 with an IC50 of 11 nM.
  • Affects CXCL2-induced intraluminal crawling of neutrophils.
  • Thwarts intraluminal crawling of adherent neutrophils to optimal sites of emigration.
  • Significantly increases transmigration time and detachment time.
  • Inhibits the migration speed of extravascular chemotaxing neutrophils.

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