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Medchemexpress LLC SBI-553 | 1849603-72-0 | 99.7% | 450.55 | 10 MG
SDP

Supplier:  Medchemexpress LLC 10MGHY125880

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SBI-553 is a potent and brain penetrant NTR1 allosteric modulator, with an EC50 of 0.34 μM. It induces β-blocking protein recruitment and NTSR1 internalization without stimulating Gq protein activation, IP3 production, or calcium mobilization. In vivo, it alleviates cocaine- or methamphetamine-induced hyperactivity in wild-type mice. This product is for research use only.

  • Potent and brain penetrant NTR1 allosteric modulator with an EC50 of 0.34 μM
  • Induces β-blocking protein recruitment and NTSR1 internalization
  • Does not stimulate Gq protein activation, IP3 production, or calcium mobilization
  • Alleviates cocaine- or methamphetamine-induced hyperactivity in wild-type mice
  • For research use only

Catalog No. 50-003-65596


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