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Medchemexpress LLC SBI-581 | 98.2% | 383.44 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY13943910MM/1ML

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SBI-581 is an orally active and potent selective serine-threonine kinase TAO3 inhibitor with an IC50 of 42 nM. It promotes TKS5α accumulation at RAB11-positive vesicles, inhibits invadopodia formation, and shows reasonable pharmacokinetics and antitumor activity in mice. It is also a click chemistry reagent with an Alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc).

  • Promotes TKS5α accumulation at RAB11-positive vesicles
  • Inhibits invadopodia formation
  • Shows reasonable pharmacokinetics and antitumor activity in mice
  • Functions as a click chemistry reagent with an Alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc)
  • Displays moderate selectivity against a broad panel of kinases

Catalog No. 50-003-51658


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