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Enzo Life Sciences SC-236 (25mg). CAS: 170569-86-5
SDP

Supplier:  Enzo Life Sciences ALX270377M025

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COX inhibitor. Highly selective and potent inhibitor of cyclooxygenase-2 (IC50=10nM for COX-2 versus IC50=17.8µM for COX-1) with antitumor properties. Exhibits longer half-life time and reduced gastric toxicity in fasting rat model. Has antitumor properties and has been shown to induce apoptosis and bFGF and VEGF-driven angiogenesis. Potent antimetastatic activity against both spontaneous metastases arising following primary tumour excision and experimental metastases. Alternative name: 4-[5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide. Formula: C16H11ClF3N3O2S. MW: 401.8. Purity: ≥95% (HPLC). Appearance: White to off-white crystalline powder. Solubility: Soluble in DMSO. Use/Stability: Stable for at least 2 years after receipt when stored at -20°C. Stock solutions are stable for 3 months when stored at -20°C. Long Term Storage: -20°C.

Catalog No. 50-200-8519


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