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AdipoGen SCD1 ms pAb
Supplier: AdipoGen AG25A0031C100
Polyclonal Antibody. Recognizes mouse SCD1. Detects a band of ~41kDa by Western Blot. Source Rabbit. Applications ELISA, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Stearoyl-CoA desaturase SCD is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. Several SCD isoforms SCD1, -2, and -3 exist in the mouse. Mice with a targeted disruption of the SCD1 isoform had reduced body adiposity, increased insulin sensitivity, and resistance to diet-induced weight gain. The protection from obesity involved increased energy expenditure and increased oxygen consumption. SCD1 deficiency shows activation of lipid oxidation in addition to reduced triglyceride synthesis and storage.
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