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Sigma Aldrich Fine Chemicals Biosciences SCf human Animal component
Supplier: Sigma Aldrich Fine Chemicals Biosciences SRP315110UG
SCf (stem cell factor) is a hematopoietic cytokine that exists in both soluble and transmembrane forms which arise due to alternative splicing. Both these forms are functionally active. This gene is localized to human chromosome 12q22-12q24. Endothelial cells and fibroblasts constitutively produce both transmembrane and soluble forms of SCf. It is also produced by keratinocytes in normal skin and epithelial cells in the gut and thymus. Recombinant human SCf is an 18.4 kDa polypeptide containing 165 amino acid residues which corresponds to the sequence of the secreted soluble form of SCf.
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